Comparison of healing effectiveness of different debridement approaches for diabetic foot ulcers: a network meta-analysis of randomized controlled trials
Peng Ning, Yupu Liu, Jun Kang, Hongyi Cao, Jiaxing Zhang · 2023
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Description
Peng Ning and co-authors compare ways to clean diabetic foot ulcers, a step that strongly shapes healing. Their 2023 network meta-analysis pools randomized trials of debridement methods, which range from sharp cutting to enzyme creams that digest dead tissue.
Nineteen trials with nine hundred patients entered the pool. An enzyme fraction from a mountain papaya latex ranked best for full healing, ahead of standard care. A kiwifruit extract ranked best for shrinking ulcer area. Overall, enzyme-based cleaning beat the other methods on both scores. The authors note that trial quality was low, so they advise enzyme methods as an add-on beside sharp debridement rather than a full replacement in daily care.
Catalog record
| CREATOR | Peng Ning, Yupu Liu, Jun Kang, Hongyi Cao, Jiaxing Zhang |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |