HPLC method for quantifying verbascoside in Stizophyllum perforatum and assessment of verbascoside acute toxicity and antileishmanial activity
Osvaine Junior Alvarenga Alves, Saulo Duarte Ozelin, Larissa Fernandes Magalhães, Ana Carolina Bolela Bovo Candido, Valéria Maria Melleiro Gimenez, Márcio Luís Andrade e Silva, Wilson Roberto Cunha, Ana Helena Januário, Denise Crispim Tavares, Lizandra Guidi Magalhães, Patricia Mendonça Pauletti · 2023
Read HPLC method for quantifying verbascoside in Stizophyllum perforatum and assessment of verbascoside acute toxicity and antileishmanial activity by Osvaine Junior Alvarenga Alves, Saulo Duarte Ozelin, Larissa Fernandes Magalhães, Ana Carolina Bolela Bovo Candido, Valéria Maria Melleiro Gimenez, Márcio Luís Andrade e Silva, Wilson Roberto Cunha, Ana Helena Januário, Denise Crispim Tavares, Lizandra Guidi Magalhães, Patricia Mendonça Pauletti (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10749199.txt.
Description
Osvaine Junior Alvarenga Alves and colleagues published a 2023 laboratory study of a South American plant in the bignonia family. The team focused on verbascoside, a compound they found to be the main ingredient in extracts of the plant's leaves. They also built a reliable lab method to measure exactly how much of it an extract contains.
Safety testing in animals suggested the extract was well tolerated at high doses. Both the leaf extracts and the isolated compounds showed activity against the parasites that cause leishmaniasis, a neglected tropical disease. The measurement method gives future researchers a standard way to check the strength of preparations made from this plant.
Catalog record
| CREATOR | Osvaine Junior Alvarenga Alves, Saulo Duarte Ozelin, Larissa Fernandes Magalhães, Ana Carolina Bolela Bovo Candido, Valéria Maria Melleiro Gimenez, Márcio Luís Andrade e Silva, Wilson Roberto Cunha, Ana Helena Januário, Denise Crispim Tavares, Lizandra Guidi Magalhães, Patricia Mendonça Pauletti |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |