The proteomic fingerprint in infants with single ventricle heart disease in the interstage period: evidence of chronic inflammation and widespread activation of biological networks
Lindsay M. Thomson, Christopher A. Mancuso, Kelly R. Wolfe, Ludmila Khailova, Sierra Niemiec, Eiman Ali, Michael DiMaria, Max Mitchell, Mark Twite, Gareth Morgan, Benjamin S. Frank, Jesse A. Davidson · 2023
Read The proteomic fingerprint in infants with single ventricle heart disease in the interstage period: evidence of chronic inflammation and widespread activation of biological networks by Lindsay M. Thomson, Christopher A. Mancuso, Kelly R. Wolfe, Ludmila Khailova, Sierra Niemiec, Eiman Ali, Michael DiMaria, Max Mitchell, Mark Twite, Gareth Morgan, Benjamin S. Frank, Jesse A. Davidson (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10748388.txt.
Description
Thomson and co-authors map blood proteins in infants with single ventricle heart disease. Babies born with one working ventricle face illness across many body systems. The interstage period, between early surgeries, is a fragile time when close watch matters most for these infants.
Protein profiling of their blood gave a distinct fingerprint for this stage. The pattern showed signs of ongoing inflammation across the body. It also showed wide activation of biological networks, far beyond the heart alone. Such a fingerprint may help doctors spot infants at higher risk and time extra care.
Catalog record
| CREATOR | Lindsay M. Thomson, Christopher A. Mancuso, Kelly R. Wolfe, Ludmila Khailova, Sierra Niemiec, Eiman Ali, Michael DiMaria, Max Mitchell, Mark Twite, Gareth Morgan, Benjamin S. Frank, Jesse A. Davidson |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |