Long-Term Analyses of SARS-CoV-2 Humoral and T Cell Responses and Breakthrough SARS-CoV-2 Infections after Two Doses of BNT162b2 Followed by mRNA-1273 and Bivalent Omicron-Adapted BNT162b2 Vaccines: A Prospective Study over 2 Years in Non-Immunocompromised Individuals
Alejo Erice, Lola Prieto, Cristina Caballero, Luis Martinez-Sobrido · 2023
Read Long-Term Analyses of SARS-CoV-2 Humoral and T Cell Responses and Breakthrough SARS-CoV-2 Infections after Two Doses of BNT162b2 Followed by mRNA-1273 and Bivalent Omicron-Adapted BNT162b2 Vaccines: A Prospective Study over 2 Years in Non-Immunocompromised Individuals by Alejo Erice, Lola Prieto, Cristina Caballero, Luis Martinez-Sobrido (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10748336.txt.
Description
Vaccine responses and breakthrough infections are tracked for two years by Alejo Erice and co-authors in a 2023 prospective study. The catalog creator adds a fourth author whom the head byline omits, so team framing is used. Long-term analysis of immune responses after SARS-CoV-2 messenger RNA vaccines is essential for sound vaccination strategy, as protection and its durability shape booster policy worldwide.
A cohort of healthy adults was followed for over two years after two doses of one vaccine. Antibodies against the spike receptor-binding domain were measured at eight time points, and T cell responses by an interferon release assay. Most participants later received a different booster, and a third received a bivalent Omicron-adapted shot. Breakthrough infections were common during follow-up.
Catalog record
| CREATOR | Alejo Erice, Lola Prieto, Cristina Caballero, Luis Martinez-Sobrido |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |