Synthesis, Pharmacological Properties, and Potential Molecular Mechanisms of Antitumor Activity of Betulin and Its Derivatives in Gastrointestinal Cancers
Marcel Madej, Joanna Gola, Elwira Chrobak, Gabriele Grassi · 2023
Read Synthesis, Pharmacological Properties, and Potential Molecular Mechanisms of Antitumor Activity of Betulin and Its Derivatives in Gastrointestinal Cancers by Marcel Madej, Joanna Gola, Elwira Chrobak, Gabriele Grassi (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10748330.txt.
Description
Marcel Madej and co-authors review betulin, a natural compound from birch bark, and its derivatives as candidate drugs against gastrointestinal cancers. Published in 2023, the review covers synthesis, pharmacological properties, and the molecular routes by which these compounds may fight tumors. Such cancers are growing more common worldwide, tied in part to unhealthy lifestyles, and treatment options remain limited.
Betulin leads a search for new antitumor compounds from natural sources. The authors gather what is known about how it and its chemical offshoots act on cancer cells in gut related organs. The review aims to map both the promise and the gaps for this compound family, as a base for drug development work.
Catalog record
| CREATOR | Marcel Madej, Joanna Gola, Elwira Chrobak, Gabriele Grassi |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |