Unveiling the Pain Relief Potential: Harnessing Analgesic Peptides from Animal Venoms
Ana Flávia Marques Pereira, Joeliton S. Cavalcante, Davi Gomes Angstmam, Cayo Almeida, Gean S. Soares, Manuela B. Pucca, Rui Seabra Ferreira Junior · 2023
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Description
Ana Flávia Marques Pereira and co-authors review animal venoms as a source of new pain drugs. Their 2023 paper surveys toxins from snakes, spiders and other arthropods, mollusks, and backboned animals, many of which block pain in lab models of very different kinds.
Pain mixes sensation and emotion and comes in forms that range from brief to lifelong, which makes it hard to treat well. The review picks out the most promising venom compounds as templates for drug design and weighs the hurdles ahead, from safety to delivery. The authors favor mixed therapy that combines several agents at once. They argue that venom chemistry remains one of the richest untapped stores for pain relief research.
Catalog record
| CREATOR | Ana Flávia Marques Pereira, Joeliton S. Cavalcante, Davi Gomes Angstmam, Cayo Almeida, Gean S. Soares, Manuela B. Pucca, Rui Seabra Ferreira Junior |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |