Molecular Mechanisms of Ferroptosis and Its Role in Viral Pathogenesis

Riwei Huang, Jiang Wu, Yaodan Ma, Kai Kang, Bumsuk Hahm · 2023

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Description

Riwei Huang and co-authors review a form of cell death driven by iron and its role in virus disease. Their review from 2023 calls the process ferroptosis. It is marked by iron build up and by damage to cell fats from oxygen, and its paths run through iron, fat, and amino acid handling.

Viruses have evolved to twist this process for their own ends. Some use it to help copy themselves inside host cells, while the host may use it in defense. The review sets out the core paths of the death process and then traces how viral infections exploit it. The authors argue that this map can guide new anti virus drugs and better care.

Catalog record

CREATORRiwei Huang, Jiang Wu, Yaodan Ma, Kai Kang, Bumsuk Hahm
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE54 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10747891

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