Triple-Emulsion-Based Antibubbles: A Step Forward in Fabricating Novel Multi-Drug Delivery Systems

Rabia Zia, Albert T. Poortinga, Akmal Nazir, Salahdein Aburuz, Cornelus F. van Nostrum · 2023

Read Triple-Emulsion-Based Antibubbles: A Step Forward in Fabricating Novel Multi-Drug Delivery Systems by Rabia Zia, Albert T. Poortinga, Akmal Nazir, Salahdein Aburuz, Cornelus F. van Nostrum (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747882.txt.

Description

Zia and co-authors build a new kind of antibubble that can carry both water-loving and fat-loving drugs at once. Antibubbles are droplets with a water-air-water structure, a fresh form of capsule. Their older versions lost the oily layer during making, so fatty cargo had no home. The new design starts from a triple emulsion with an oil layer kept inside. The inner water phase holds a nanoemulsion steadied by food proteins. Whey, soy, and pea proteins were each tried.

Dyes stood in as model drugs to test loading. The structure promises one carrier for mixed drug pairs. Such pairs are common in therapy but hard to package together.

Catalog record

CREATORRabia Zia, Albert T. Poortinga, Akmal Nazir, Salahdein Aburuz, Cornelus F. van Nostrum
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10747882

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