Effectiveness of Adapted COVID-19 Vaccines and Ability to Establish Herd Immunity against Omicron BA.1 and BA4-5 Variants of SARS-CoV-2

Pedro Plans-Rubió · 2023

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Description

Pedro Plans-Rubió judges updated COVID-19 vaccines against Omicron strains in a 2023 study. New variants raised fair doubts about whether booster campaigns could build herd immunity. Adapted vaccines were tuned to Omicron lines, first the early one and then later subvariants.

A systematic review pooled absolute effectiveness against infection from the literature. Herd prospects were then weighed with spread rates and non-drug measures in the mix. Meta-analysis supplied the core effectiveness figures for both variant waves. A vaccine can protect its taker yet still fall short of herd thresholds. That split verdict is the sober heart of the study.

Catalog record

CREATORPedro Plans-Rubió
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10747774

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