Physiologically Based Pharmacokinetic Modelling of Cabotegravir Microarray Patches in Rats and Humans
Hannah Kinvig, Rajith K R Rajoli, Henry Pertinez, Lalitkumar K Vora, Fabiana Volpe-Zanutto, Ryan F Donnelly, Steve Rannard, Charles Flexner, Marco Siccardi, Andrew Owen, Elżbieta Wyska · 2023
Read Physiologically Based Pharmacokinetic Modelling of Cabotegravir Microarray Patches in Rats and Humans by Hannah Kinvig, Rajith K R Rajoli, Henry Pertinez, Lalitkumar K Vora, Fabiana Volpe-Zanutto, Ryan F Donnelly, Steve Rannard, Charles Flexner, Marco Siccardi, Andrew Owen, Elżbieta Wyska (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747499.txt.
Description
Hannah Kinvig, Rajith Rajoli, and co-authors model how a skin patch dose of an HIV guard drug would run in rats and folks, in a 2023 study. Patch pads give a pain free self dose path for long drug guard. Week patch doses had to be sized by maths past rat and shot data.
A body maths frame takes the patch in with fit terms from past runs. Rat patch and shot data check the frame, plus folk shot data as well. Week patch sizes from small to large hold blood marks past guard lines. Two large sizes pass the high guard line too. Patch paths look fit for more work.
Catalog record
| CREATOR | Hannah Kinvig, Rajith K R Rajoli, Henry Pertinez, Lalitkumar K Vora, Fabiana Volpe-Zanutto, Ryan F Donnelly, Steve Rannard, Charles Flexner, Marco Siccardi, Andrew Owen, Elżbieta Wyska |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |