A Hydrolase Produced by Rhodococcus erythropolis HQ Is Responsible for the Detoxification of Zearalenone
Junqiang Hu, Shilong Du, Han Qiu, Yuzhuo Wu, Qing Hong, Gang Wang, Sherif Ramzy Mohamed, Yin-Won Lee, Jianhong Xu · 2023
Read A Hydrolase Produced by Rhodococcus erythropolis HQ Is Responsible for the Detoxification of Zearalenone by Junqiang Hu, Shilong Du, Han Qiu, Yuzhuo Wu, Qing Hong, Gang Wang, Sherif Ramzy Mohamed, Yin-Won Lee, Jianhong Xu (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747462.txt.
Description
Junqiang Hu and co-authors found a soil bacterium that can destroy a troublesome food toxin. Their 2023 study targets zearalenone, a mold poison that mimics estrogen and turns up in grain for people and livestock. The bacterium, a strain of Rhodococcus erythropolis, was pulled from soil and set against the toxin.
The team traced the cleanup to one gene, zenR, whose product is an enzyme named ZenR. The enzyme works best in warm, mildly alkaline settings and runs nearly three times as fast as a known cousin enzyme. Its active core was pinned to three amino acids. Grown in another bacterium, ZenR cleared ninety-three percent of the toxin from liquefied corn. The authors offer it as a template for industrial detox.
Catalog record
| CREATOR | Junqiang Hu, Shilong Du, Han Qiu, Yuzhuo Wu, Qing Hong, Gang Wang, Sherif Ramzy Mohamed, Yin-Won Lee, Jianhong Xu |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |