Spray-Dried Powder Containing Cannabigerol: A New Extemporaneous Emulgel for Topical Administration

Alice Picco, Lorena Segale, Ivana Miletto, Federica Pollastro, Silvio Aprile, Monica Locatelli, Elia Bari, Maria Luisa Torre, Lorella Giovannelli · 2023

Read Spray-Dried Powder Containing Cannabigerol: A New Extemporaneous Emulgel for Topical Administration by Alice Picco, Lorena Segale, Ivana Miletto, Federica Pollastro, Silvio Aprile, Monica Locatelli, Elia Bari, Maria Luisa Torre, Lorella Giovannelli (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747370.txt.

Description

Alice Picco and co-authors turned a cannabis compound into a skin product that pharmacists can prepare fresh from a dry powder. The compound, cannabigerol or CBG, calms inflammation and fights microbes and oxidation, much like the better-known CBD. The team first tested how well CBG crosses lab-made skin-like membranes, with and without a helper molecule that boosts passage.

They then spray-dried the winning mixture into a powder that turns back into a smooth oil-in-gel cream when stirred with pure water. A battery of tests confirmed the drying step left the compound chemically unchanged. The authors offer the powder as a measured-dose form for local treatment of skin problems such as acne and psoriasis.

Catalog record

CREATORAlice Picco, Lorena Segale, Ivana Miletto, Federica Pollastro, Silvio Aprile, Monica Locatelli, Elia Bari, Maria Luisa Torre, Lorella Giovannelli
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10747370

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