Pathophysiology of Childhood-Onset Myasthenia: Abnormalities of Neuromuscular Junction and Autoimmunity and Its Background
Masatoshi Hayashi · 2023
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Description
Masatoshi Hayashi reviews childhood myasthenia in a 2023 paper. The disease weakens muscles when the immune system attacks the junction between nerve and muscle, breaking the signal that makes fibers contract. Adult research drives most care today. Yet children differ in growth and immune background, and Japan sees many cases start in early childhood.
Age patterns differ between East Asia and Western Europe. Genetic background shapes both the autoimmune form and inherited junction syndromes, and the two may overlap. Treatment choices also vary by region. Readers get a call for child-specific research on causes, course, and care.
Catalog record
| CREATOR | Masatoshi Hayashi |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |