Regulatory Effect of Ficus carica Latex on Cell Cycle Progression in Human Papillomavirus-Positive Cervical Cancer Cell Lines: Insights from Gene Expression Analysis
Muharrem Okan Cakir, Ugur Bilge, Arshia Ghanbari, G. Hossein Ashrafi · 2023
Read Regulatory Effect of Ficus carica Latex on Cell Cycle Progression in Human Papillomavirus-Positive Cervical Cancer Cell Lines: Insights from Gene Expression Analysis by Muharrem Okan Cakir, Ugur Bilge, Arshia Ghanbari, G. Hossein Ashrafi (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747314.txt.
Description
Muharrem Okan Cakir and co-authors test fig latex on cervical cancer cells in a 2023 study. Cervical cancer is a major global burden, and high-risk papillomaviruses cause most cases. Current care can clear lesions but struggles to stop spread without harming tissue. Fig tree latex has shown anti-cancer hints in lab work, yet its mechanism was unknown.
The team treated two virus-positive cancer cell lines with the latex and sequenced their RNA. Gene activity shifted in pathways that govern the cell cycle, a quality-control route for faulty messages, a master tumor suppressor, and programmed cell death. The pattern suggests the latex slows cancer growth by rewiring several core programs at once. The study maps where to probe next for a safer therapy.
Catalog record
| CREATOR | Muharrem Okan Cakir, Ugur Bilge, Arshia Ghanbari, G. Hossein Ashrafi |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |