Neutralization Determinants on Poxviruses
Vernuccio Riccardo, Guardado-Calvo Pablo · 2023
Read Neutralization Determinants on Poxviruses by Vernuccio Riccardo, Guardado-Calvo Pablo (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747254.txt.
Description
Two reviewers surveyed this 2023 topic on how antibodies disarm poxviruses. Smallpox killed millions before vaccine campaigns wiped it out in 1980. Immunity from that era has faded, and the 2022 mpox outbreak, which reached over one hundred countries, revived fears of pox threats. Modern subunit vaccines need the right targets.
The review covers the six main surface proteins that blocking antibodies aim at. For each, it maps where on the protein the antibodies land. Those maps show which pieces a vaccine must include to raise strong protection. The authors draw on structural biology to guide new vaccine design. The work serves teams building safer, targeted vaccines against a complex virus family.
Catalog record
| CREATOR | Vernuccio Riccardo, Guardado-Calvo Pablo |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |