Phospholipase C Zeta 1 (PLCZ1): The Function and Potential for Fertility Assessment and In Vitro Embryo Production in Cattle and Horses
Raul A Gonzalez-Castro, Elaine M Carnevale, Junwei Li, Inmaculada Parrilla Riera, Athina Basioura · 2023
Read Phospholipase C Zeta 1 (PLCZ1): The Function and Potential for Fertility Assessment and In Vitro Embryo Production in Cattle and Horses by Raul A Gonzalez-Castro, Elaine M Carnevale, Junwei Li, Inmaculada Parrilla Riera, Athina Basioura (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747197.txt.
Description
Raul Gonzalez-Castro and colleagues review a sperm protein, PLCZ1, that wakes the egg at fertilization. Once sperm and egg fuse, this protein sets off calcium pulses that start development. When it fails, eggs stay dormant, a leading cause of failed assisted fertilization in men.
Most knowledge comes from men and mice. The review asks what it means for cattle and horses. Horse sperm rich in the protein cleaves eggs better after injection procedures. Bull sperm, by contrast, struggles to trigger the pulses at all. In mice, injecting the protein rescues failed eggs fully. The authors call for standard tests and safety work before farm use.
Catalog record
| CREATOR | Raul A Gonzalez-Castro, Elaine M Carnevale, Junwei Li, Inmaculada Parrilla Riera, Athina Basioura |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |