Titanium Dioxide (TiO2) Nanoparticle Toxicity in a Caenorhabditis elegans Model

Sen-Ting Huang, Jian-He Lu, Sherwin M Jualo, Lemmuel L Tayo, Wan-Nurdiyana-Wan Mansor, Yi-Chieh Lai, Chih-Lung Wang, How-Ran Chao, Demetrio Raldúa, Xiaojun Luo · 2023

Read Titanium Dioxide (TiO2) Nanoparticle Toxicity in a Caenorhabditis elegans Model by Sen-Ting Huang, Jian-He Lu, Sherwin M Jualo, Lemmuel L Tayo, Wan-Nurdiyana-Wan Mansor, Yi-Chieh Lai, Chih-Lung Wang, How-Ran Chao, Demetrio Raldúa, Xiaojun Luo (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10747172.txt.

Description

Sen-Ting Huang and co-authors report a 2023 study on the toxicity of titanium dioxide nanoparticles in a tiny worm used as a lab model. The compound fills foods, cosmetics, and paints, yet its nano form may harm people and nature. The worms let the team test two forms at once: a shop-bought form and one made in the lab.

Worms were exposed to a range of doses in water. Survival and body length held steady at all doses for both forms. Breeding output and movement, in body bends and head thrashes, fell as dose rose, and lifespan shortened. A panel of stress and detox genes switched on more strongly, most of all for the shop-bought form at a mid dose. That form looks the more toxic of the two in this model.

Catalog record

CREATORSen-Ting Huang, Jian-He Lu, Sherwin M Jualo, Lemmuel L Tayo, Wan-Nurdiyana-Wan Mansor, Yi-Chieh Lai, Chih-Lung Wang, How-Ran Chao, Demetrio Raldúa, Xiaojun Luo
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10747172

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