Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis
Lukas Korf, Xing Ye, Marian S. Vogt, Wieland Steinchen, Mohamed Watad, Chris van der Does, Maxime Tourte, Shamphavi Sivabalasarma, Sonja-Verena Albers, Lars-Oliver Essen · 2023
Read Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis by Lukas Korf, Xing Ye, Marian S. Vogt, Wieland Steinchen, Mohamed Watad, Chris van der Does, Maxime Tourte, Shamphavi Sivabalasarma, Sonja-Verena Albers, Lars-Oliver Essen (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10746158.txt.
Description
Three GPN-loop GTPases, GPN1–GPN3, are central to the maturation and trafficking of eukaryotic RNA polymerase II. This GTPase family is widely represented in archaea but typically occurs as single paralogs. Structural analysis of the GTP- and GDP-bound states of the Sulfolobus acidocaldarius GPN enzyme (SaGPN) showed that this central GPN-loop GTPase adopts two distinct quaternary structures.
Catalog record
| CREATOR | Lukas Korf, Xing Ye, Marian S. Vogt, Wieland Steinchen, Mohamed Watad, Chris van der Does, Maxime Tourte, Shamphavi Sivabalasarma, Sonja-Verena Albers, Lars-Oliver Essen |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |