Two New Compounds from the Endophytic Fungi of Dryopteris crassirhizoma and Their Antimicrobial Activities
Ping Hai, Yuan Gao, Lian Yang, Nie Chen, Haiyan Jia, Mengdie Wang, Huan Li, Wenli Jiang, Jian Yang, Rongtao Li, Rosanna Mallamaci, Filomena Conforti · 2023
Read Two New Compounds from the Endophytic Fungi of Dryopteris crassirhizoma and Their Antimicrobial Activities by Ping Hai, Yuan Gao, Lian Yang, Nie Chen, Haiyan Jia, Mengdie Wang, Huan Li, Wenli Jiang, Jian Yang, Rongtao Li, Rosanna Mallamaci, Filomena Conforti (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10745856.txt.
Description
Ping Hai and co-authors search fungi that live inside a fern root for new germ-fighting compounds, in a 2023 paper. Two fungi were grown from the fresh root of Dryopteris crassirhizoma, a fern used in traditional medicine. Chemical work on the fungi yielded two new phenol compounds, plus more than twenty known compounds.
The team settled the shapes of the new compounds with several lab methods and by comparison with past reports. Two known compounds strongly slowed a test bacterium at low doses. Two others moderately slowed several plant disease fungi and important clinical bacteria. The authors say this is the first report of such compounds from fungi inside this fern. They offer the active compounds as leads for new antibacterial drugs, which are badly needed as resistance grows.
Catalog record
| CREATOR | Ping Hai, Yuan Gao, Lian Yang, Nie Chen, Haiyan Jia, Mengdie Wang, Huan Li, Wenli Jiang, Jian Yang, Rongtao Li, Rosanna Mallamaci, Filomena Conforti |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |