HLA-DQ2/8 and COVID-19 in Celiac Disease: Boon or Bane

Aaron Lerner, Carina Benzvi, Aristo Vojdani, Elisabetta Caselli · 2023

Read HLA-DQ2/8 and COVID-19 in Celiac Disease: Boon or Bane by Aaron Lerner, Carina Benzvi, Aristo Vojdani, Elisabetta Caselli (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10745744.txt.

Description

People with coeliac disease seemed, oddly, to dodge the worst of COVID-19. Lerner and co-authors test a gene tale for that luck in 2023. Coeliac patients carry two gene forms that grip virus scraps in a set groove, and the grip may be primed by past colds.

The team lines up scraps of the new virus against scraps of four old cold viruses. Matches hint at cross-trained guard cells, left by the colds and ready for the cousin. Grip strength of each scrap in the groove is scored by machine. If the tale holds, a risk gene for one disease is a shield in another. The work is all in silico, a map for bench checks.

Catalog record

CREATORAaron Lerner, Carina Benzvi, Aristo Vojdani, Elisabetta Caselli
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10745744

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