UHPLC-MS-Based Metabolomics Reveal the Potential Mechanism of Armillaria mellea Acid Polysaccharide in and Its Effects on Cyclophosphamide-Induced Immunosuppressed Mice

Ying Li, Qingqing Li, Huazhou Niu, Hui Li, Lili Jiao, Wei Wu · 2023

Read UHPLC-MS-Based Metabolomics Reveal the Potential Mechanism of Armillaria mellea Acid Polysaccharide in and Its Effects on Cyclophosphamide-Induced Immunosuppressed Mice by Ying Li, Qingqing Li, Huazhou Niu, Hui Li, Lili Jiao, Wei Wu (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10745530.txt.

Description

Ying Li and co-authors probe how an acid sugar fraction from a honey fungus boosts a weakened immune system, in a 2023 paper. The catalog title garbles the wording, so the draft follows the head. The fungus is eaten and used in supplements, and its sugars are a main active part.

In lab immune cells the purified fraction raised key immune signals and switched on a known sensing pathway. In mice whose immunity was suppressed by a drug, the same protein changes showed in the spleen. A broad chemical scan of blood found six body compounds the fraction shifted, tied to pathways that may mark its effect. The work sketches how the sugar could treat immune weakness.

Catalog record

CREATORYing Li, Qingqing Li, Huazhou Niu, Hui Li, Lili Jiao, Wei Wu
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10745530

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