Natural Product Cordycepin (CD) Inhibition for NRP1/CD304 Expression and Possibly SARS-CoV-2 Susceptibility Prevention on Cancers
Ting Li, Na Luo, Jiewen Fu, Jiaman Du, Zhiying Liu, Qi Tan, Meiling Zheng, Jiayue He, Jingliang Cheng, Dabing Li, Junjiang Fu, Qibin Geng · 2023
Read Natural Product Cordycepin (CD) Inhibition for NRP1/CD304 Expression and Possibly SARS-CoV-2 Susceptibility Prevention on Cancers by Ting Li, Na Luo, Jiewen Fu, Jiaman Du, Zhiying Liu, Qi Tan, Meiling Zheng, Jiayue He, Jingliang Cheng, Dabing Li, Junjiang Fu, Qibin Geng (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10745444.txt.
Description
Ting Li and co-authors test, in a 2023 study, if a natural product from a fungus can curb a cell gate used by cancers and by the COVID virus. The gate, NRP1, helps blood vessel growth signals and also lets the virus in. The product, cordycepin, comes from Cordyceps fungi used in Chinese medicine. Lab tests read the gate's level in cancer cells dosed with the product. A shape fit checked how the two bind. A cell test with a fake virus then gauged entry block.
The product cut the gate's level in cancer cells and stopped fake virus cell fusion. Data base reads tied the gate's level to immune traits in most cancers. The team casts the product as a dual hope: anti-cancer and anti-virus in one.
Catalog record
| CREATOR | Ting Li, Na Luo, Jiewen Fu, Jiaman Du, Zhiying Liu, Qi Tan, Meiling Zheng, Jiayue He, Jingliang Cheng, Dabing Li, Junjiang Fu, Qibin Geng |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |