Long-Acting Cabotegravir/Rilpivirine Concentrations in Combination With Intravenous Rifampin: A Case Report

Shawnalyn W Sunagawa, Joshua P Havens, Anthony Podany, Bryan Walker, Kimberly K Scarsi, Sara H Bares · 2023

Read Long-Acting Cabotegravir/Rilpivirine Concentrations in Combination With Intravenous Rifampin: A Case Report by Shawnalyn W Sunagawa, Joshua P Havens, Anthony Podany, Bryan Walker, Kimberly K Scarsi, Sara H Bares (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10745268.txt.

Description

Shawnalyn Sunagawa and co-authors report a drug clash in HIV care in a 2023 case paper. A patient on long-acting injectable cabotegravir and rilpivirine also received intravenous rifampin, a strong antibiotic. Rifampin is known to speed the breakdown of many drugs. Blood checks showed both HIV drug levels sinking below four times the adjusted potency threshold, the zone where the virus may escape control. The case warns teams to check interactions before pairing long-acting therapy with rifampin.

Catalog record

CREATORShawnalyn W Sunagawa, Joshua P Havens, Anthony Podany, Bryan Walker, Kimberly K Scarsi, Sara H Bares
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE11 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10745268

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