Circle of Willis Configuration and Thrombus Localization Impact on Ischemic Stroke Patient Outcomes: A Systematic Review
Audrius Širvinskas, Givi Lengvenis, Giedrius Ledas, Valerija Mosenko, Saulius Lukoševičius, Anna Podlasek, Iris Quasar Grunwald · 2023
Read Circle of Willis Configuration and Thrombus Localization Impact on Ischemic Stroke Patient Outcomes: A Systematic Review by Audrius Širvinskas, Givi Lengvenis, Giedrius Ledas, Valerija Mosenko, Saulius Lukoševičius, Anna Podlasek, Iris Quasar Grunwald (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10744990.txt.
Description
Audrius Sirvinskas and co-authors reviewed how the brain's backup blood network affects stroke outcomes in a 2023 paper. That network, the Circle of Willis, can reroute blood when a vessel blocks. The team searched major databases for studies on its shape and on clot location, then scored their quality. Eleven studies covering thousands of patients made the final set.
An intact circle mattered most when the blockage sat at the end of the main brain artery in a T shape. There, a fully formed segment on the opposite side and the connecting artery were essential for a good outcome. For blockages one branch further along, the circle's shape mattered little. The authors conclude that a complete circle supports collateral flow and better recovery, since it decides how much brain is at risk.
Catalog record
| CREATOR | Audrius Širvinskas, Givi Lengvenis, Giedrius Ledas, Valerija Mosenko, Saulius Lukoševičius, Anna Podlasek, Iris Quasar Grunwald |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |