Low Urinary Free Cortisol as a Risk Factor for Patients with Variceal Bleeding
Ioanna Aggeletopoulou, Efthymios P Tsounis, Maria Kalafateli, Maria Michailidou, Maria Tsami, Konstantinos Zisimopoulos, Martha Mandellou, Georgia Diamantopoulou, Maria Kouskoura, Marina Michalaki, Catherine K Markopoulou, Konstantinos Thomopoulos, Christos Triantos, Giovanni Tarantino · 2023
Read Low Urinary Free Cortisol as a Risk Factor for Patients with Variceal Bleeding by Ioanna Aggeletopoulou, Efthymios P Tsounis, Maria Kalafateli, Maria Michailidou, Maria Tsami, Konstantinos Zisimopoulos, Martha Mandellou, Georgia Diamantopoulou, Maria Kouskoura, Marina Michalaki, Catherine K Markopoulou, Konstantinos Thomopoulos, Christos Triantos, Giovanni Tarantino (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10744924.txt.
Description
Ioanna Aggeletopoulou leads a large team in this 2023 study on a urine test that may flag danger in liver patients who bleed from swollen veins. In cirrhosis, the adrenal glands can underperform, and free cortisol is the truest gauge of that shortfall, yet it is costly to measure directly. The team compared cortisol readings across blood, saliva, and a day's urine in forty bleeding patients.
The urine measure tracked free blood cortisol well. It also ran lower in patients with worse liver scores and higher inflammation. Patients who rebled, caught infection, or died showed lower urine cortisol. Liver stage itself predicted six-week death, and a clotted portal vein predicted early treatment failure. The authors propose urine cortisol as a cheap risk marker worth larger trials in this fragile group.
Catalog record
| CREATOR | Ioanna Aggeletopoulou, Efthymios P Tsounis, Maria Kalafateli, Maria Michailidou, Maria Tsami, Konstantinos Zisimopoulos, Martha Mandellou, Georgia Diamantopoulou, Maria Kouskoura, Marina Michalaki, Catherine K Markopoulou, Konstantinos Thomopoulos, Christos Triantos, Giovanni Tarantino |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |