Association between Gray and White Matter Lesions and Its Involvement in Clinical Symptoms of Alzheimer’s-Type Dementia
Taizen Nakase, Benjamin Thyreau, Yasuko Tatewaki, Naoki Tomita, Yumi Takano, Michiho Muranaka, Yasuyuki Taki, Elliott J Mufson, Muh-Shi Lin, Andrew Chih Wei Huang, Seong Soo A An, Bai Chuang Shyu, Anna Kozłowska · 2023
Read Association between Gray and White Matter Lesions and Its Involvement in Clinical Symptoms of Alzheimer’s-Type Dementia by Taizen Nakase, Benjamin Thyreau, Yasuko Tatewaki, Naoki Tomita, Yumi Takano, Michiho Muranaka, Yasuyuki Taki, Elliott J Mufson, Muh-Shi Lin, Andrew Chih Wei Huang, Seong Soo A An, Bai Chuang Shyu, Anna Kozłowska (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10744158.txt.
Description
Taizen Nakase and colleagues examine how two kinds of brain lesion conspire in the symptoms of Alzheimer-type dementia, in this study from twenty twenty-three. Gray matter loss is the famous damage. White matter lesions, scars in the wiring, are the quieter partner. One hundred fifty-six memory clinic patients, with dementia or its amnestic prelude, had both blood-flow scans and MRI.
The pairing mattered, symptom by symptom. Disorientation and poor attention tracked with the precuneus region together with white matter lesions in both hemispheres. Hyperactivity, a behavioral symptom, linked frontal gray matter on both sides with the white matter damage. Patients at the earlier, milder stage actually showed more of these cross-lesion ties than full dementia patients. The authors read dementia's symptoms as duets between tissue loss and wire damage, changing as the disease advances.
Catalog record
| CREATOR | Taizen Nakase, Benjamin Thyreau, Yasuko Tatewaki, Naoki Tomita, Yumi Takano, Michiho Muranaka, Yasuyuki Taki, Elliott J Mufson, Muh-Shi Lin, Andrew Chih Wei Huang, Seong Soo A An, Bai Chuang Shyu, Anna Kozłowska |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |