The Non-Invasive Prediction of Colorectal Neoplasia (NIPCON) Study 1995–2022: A Comparison of Guaiac-Based Fecal Occult Blood Test (FOBT) and an Anti-Adenoma Antibody, Adnab-9

Martin Tobi, Fadi Antaki, Mary Ann Rambus, Yu-Xiao Yang, David Kaplan, Rebecca Rodriguez, Benedict Maliakkal, Adhip Majumdar, Ereny Demian, Yosef Y Tobi, Paula Sochacki, Murray Ehrinpreis, Michael G Lawson, Benita McVicker, Cristina Peña · 2023

Read The Non-Invasive Prediction of Colorectal Neoplasia (NIPCON) Study 1995–2022: A Comparison of Guaiac-Based Fecal Occult Blood Test (FOBT) and an Anti-Adenoma Antibody, Adnab-9 by Martin Tobi, Fadi Antaki, Mary Ann Rambus, Yu-Xiao Yang, David Kaplan, Rebecca Rodriguez, Benedict Maliakkal, Adhip Majumdar, Ereny Demian, Yosef Y Tobi, Paula Sochacki, Murray Ehrinpreis, Michael G Lawson, Benita McVicker, Cristina Peña (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10743815.txt.

Description

Martin Tobi and co-authors compare two stool tests for predicting colorectal growths in work from 2023. The long study, running from 1995 to 2022, aims to improve non-invasive detection of adenomas, the growths that can turn into cancer.

One test is the standard guaiac blood test; the other uses an antibody raised against adenoma tissue. The antibody test was far more sensitive for adenomas, advanced adenomas, and both combined. Signals differed by colon region and by ancestry in one site. The authors conclude the antibody test could better direct colonoscopy screening.

Catalog record

CREATORMartin Tobi, Fadi Antaki, Mary Ann Rambus, Yu-Xiao Yang, David Kaplan, Rebecca Rodriguez, Benedict Maliakkal, Adhip Majumdar, Ereny Demian, Yosef Y Tobi, Paula Sochacki, Murray Ehrinpreis, Michael G Lawson, Benita McVicker, Cristina Peña
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10743815

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