Virtual Screening Technology for Two Novel Peptides in Soybean as Inhibitors of α-Amylase and α-Glucosidase
Xiyao Tang, Xu Chen, Hong Wang, Jinyi Yang, Lin Li, Jie Zhu, Yujia Liu, Rotimi Aluko · 2023
Read Virtual Screening Technology for Two Novel Peptides in Soybean as Inhibitors of α-Amylase and α-Glucosidase by Xiyao Tang, Xu Chen, Hong Wang, Jinyi Yang, Lin Li, Jie Zhu, Yujia Liu, Rotimi Aluko (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10743026.txt.
Description
Xiyao Tang and co-authors hunt in soybean protein for short chains that slow two sugar-breaking enzymes, in work from 2023. Slowing these enzymes can blunt blood sugar spikes after meals. The team first checked that soy chains do slow both enzymes, then screened them by computer.
Two chains of eight units each, not reported before, passed the screen. Model studies showed which bonds hold them to the enzymes and which end units matter most. The team then made both chains in the lab and gauged their strength. Both slowed each enzyme at modest doses. The authors offer the chains as leads for special foods aimed at blood sugar control.
Catalog record
| CREATOR | Xiyao Tang, Xu Chen, Hong Wang, Jinyi Yang, Lin Li, Jie Zhu, Yujia Liu, Rotimi Aluko |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |