New and Old Key Players in Liver Cancer
Ángel M. Cuesta, Nerea Palao, Paloma Bragado, Alvaro Gutierrez-Uzquiza, Blanca Herrera, Aránzazu Sánchez, Almudena Porras · 2023
Read New and Old Key Players in Liver Cancer by Ángel M. Cuesta, Nerea Palao, Paloma Bragado, Alvaro Gutierrez-Uzquiza, Blanca Herrera, Aránzazu Sánchez, Almudena Porras (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10742790.txt.
Description
Liver cancer is a growing cause of death worldwide, and most cases are of one type, hepatocellular carcinoma. Ángel Cuesta and co-authors review the cells and signals that drive that cancer in this 2023 paper. The cancer usually grows in a liver already scarred by long inflammation and cirrhosis. Its cells of origin are most likely the main liver cells, though stem-like liver cells may start some cases.
The review gives special weight to platelets, the blood parts best known for clotting. Platelets can push tumors to grow or hold them back, depending on the setting and on tight control of their signals. The authors also weigh the roles of liver support cells and immune cells. Three signal paths get close attention for their part in tumor growth. The picture helps drug hunters pick targets.
Catalog record
| CREATOR | Ángel M. Cuesta, Nerea Palao, Paloma Bragado, Alvaro Gutierrez-Uzquiza, Blanca Herrera, Aránzazu Sánchez, Almudena Porras |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |