The Predictive Role of the Histopathological Scoring System in Adipose Tumors—Lipoma, Atypical Lipomatous Tumor, and Liposarcoma

Mariana Deacu, Madalina Bosoteanu, Manuela Enciu, Georgeta Camelia Cozaru, Oana Cojocaru, Gabriela Izabela Baltatescu, Anca Antonela Nicolau, Cristian Ionut Orasanu, Bogdan Marian Caraban, Raluca Ioana Voda, Gustavo Baldassarre · 2023

Read The Predictive Role of the Histopathological Scoring System in Adipose Tumors—Lipoma, Atypical Lipomatous Tumor, and Liposarcoma by Mariana Deacu, Madalina Bosoteanu, Manuela Enciu, Georgeta Camelia Cozaru, Oana Cojocaru, Gabriela Izabela Baltatescu, Anca Antonela Nicolau, Cristian Ionut Orasanu, Bogdan Marian Caraban, Raluca Ioana Voda, Gustavo Baldassarre (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10742782.txt.

Description

Fat tumors range from harmless lipomas to deadly liposarcomas, and under the microscope the middle cases can fool even experts. The authors of a 2023 study build a scoring system from ten years of cases, 112 tumors in all. They stain each tumor for two driver proteins and two vessel markers, and test the key gene directly. Clinical facts, cell features, and the density of tiny blood vessels all feed the score.

The score separates the three tumor types with high sensitivity and specificity, near perfect for lipomas and liposarcomas. Vessel density tracks how abnormal the cells look, and tumors wider than 69 millimeters more often show dead tissue. The authors offer the score as a guide for diagnosis and for predicting test results.

Catalog record

CREATORMariana Deacu, Madalina Bosoteanu, Manuela Enciu, Georgeta Camelia Cozaru, Oana Cojocaru, Gabriela Izabela Baltatescu, Anca Antonela Nicolau, Cristian Ionut Orasanu, Bogdan Marian Caraban, Raluca Ioana Voda, Gustavo Baldassarre
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10742782

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