Prophylactic Medication during Radioembolization in Metastatic Liver Disease: Is It Really Necessary? A Retrospective Cohort Study and Systematic Review of the Literature
Manon N. G. J. A. Braat, Sander C. Ebbers, Ahmed A. Alsultan, Atal O. Neek, Rutger C. G. Bruijnen, Maarten L. J. Smits, Joep de Bruijne, Marnix G. E. H. Lam, Arthur J. A. T. Braat · 2023
Read Prophylactic Medication during Radioembolization in Metastatic Liver Disease: Is It Really Necessary? A Retrospective Cohort Study and Systematic Review of the Literature by Manon N. G. J. A. Braat, Sander C. Ebbers, Ahmed A. Alsultan, Atal O. Neek, Rutger C. G. Bruijnen, Maarten L. J. Smits, Joep de Bruijne, Marnix G. E. H. Lam, Arthur J. A. T. Braat (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10742749.txt.
Description
Manon Braat and colleagues ask whether the preventive drugs given around liver radioembolization actually prevent anything, in this study from twenty twenty-three. The treatment seeds radioactive beads into liver tumors. To shield the healthy liver, many centers give a protective drug pair afterward, pentoxifylline and ursodeoxycholic acid, on habit more than evidence.
In their center's seventy patients treated for neuroendocrine or colorectal liver spread, the drugs made no difference. Fifty-one patients who received them fared no better on liver toxicity than the nineteen who did not. What did predict biochemical harm was the radiation dose absorbed by the healthy liver itself. A review of the literature, five hundred thirty-four patients across eight papers, found no consistent advice either. The authors conclude the ritual medication lacks support, and no international guideline backs it.
Catalog record
| CREATOR | Manon N. G. J. A. Braat, Sander C. Ebbers, Ahmed A. Alsultan, Atal O. Neek, Rutger C. G. Bruijnen, Maarten L. J. Smits, Joep de Bruijne, Marnix G. E. H. Lam, Arthur J. A. T. Braat |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |