Assessing the Antioxidant Benefits of Topical Carvacrol and Magnolol Periodontal Hydrogel Therapy in Periodontitis Associated with Diabetes in Wistar Rats

Georgiana Ioana Potra Cicalău, Gabriela Ciavoi, Ioana Scrobotă, Andreea Olivia Marcu, Ioana Romanul, Eleonora Marian, Laura Grațiela Vicaș, Mariana Ganea, Patrick R Schmidlin, Ioannis D Vouros · 2023

Read Assessing the Antioxidant Benefits of Topical Carvacrol and Magnolol Periodontal Hydrogel Therapy in Periodontitis Associated with Diabetes in Wistar Rats by Georgiana Ioana Potra Cicalău, Gabriela Ciavoi, Ioana Scrobotă, Andreea Olivia Marcu, Ioana Romanul, Eleonora Marian, Laura Grațiela Vicaș, Mariana Ganea, Patrick R Schmidlin, Ioannis D Vouros (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10742747.txt.

Description

Two plant compounds may ease gum disease in rats that also have diabetes, and a 2023 study by Georgiana Ioana Potra Cicalău and co-authors tests them in a gel. Both diseases feed on oxidative stress, which harms cells, and the compounds, carvacrol and magnolol, are natural antioxidants.

Ninety Wistar rats were split into nine groups covering health, each disease alone, both together, and treated sets. The gel was placed on the gums of rats with both conditions, using one compound, the other, or both. Blood tests tracked a damage marker and the activity of a protective enzyme. The study asks whether a natural gel can blunt the stress that links the two diseases.

Catalog record

CREATORGeorgiana Ioana Potra Cicalău, Gabriela Ciavoi, Ioana Scrobotă, Andreea Olivia Marcu, Ioana Romanul, Eleonora Marian, Laura Grațiela Vicaș, Mariana Ganea, Patrick R Schmidlin, Ioannis D Vouros
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10742747

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