Platelet Counts and Risk of Severe Retinopathy of Prematurity: A Bayesian Model-Averaged Meta-Analysis
Mohamad F Almutairi, Silvia Gulden, Tamara M Hundscheid, František Bartoš, Giacomo Cavallaro, Eduardo Villamor, Stefan Grosek · 2023
Read Platelet Counts and Risk of Severe Retinopathy of Prematurity: A Bayesian Model-Averaged Meta-Analysis by Mohamad F Almutairi, Silvia Gulden, Tamara M Hundscheid, František Bartoš, Giacomo Cavallaro, Eduardo Villamor, Stefan Grosek (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10741847.txt.
Description
Mohamad Almutairi and co-authors pool in 2023 the evidence on whether low blood platelet counts warn of severe eye disease in babies born too early. The disease, retinopathy of prematurity, can blind infants, and its worst forms need fast treatment. The team gathered studies that linked platelet counts, taken in the first two weeks or near treatment time, to severe disease.
Twenty-one studies went into a combined analysis that weighs evidence for and against a link. Low counts in both time windows tied to severe disease, with the later window giving the strongest signal. Very low counts near treatment time also tied to severe cases. When the team adjusted for the bias toward publishing positive results, only that last link kept moderate support. The authors present the tie as real but softer than the raw numbers suggest.
Catalog record
| CREATOR | Mohamad F Almutairi, Silvia Gulden, Tamara M Hundscheid, František Bartoš, Giacomo Cavallaro, Eduardo Villamor, Stefan Grosek |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |