HPV-Negative and HPV-Positive Oral Cancer Cells Stimulate the Polarization of Neutrophils towards Different Functional Phenotypes In Vitro

Marcela Guadalupe Martínez-Barajas, Luis Felipe Jave-Suárez, Inocencia Guadalupe Ramírez-López, Mariel García-Chagollán, José Sergio Zepeda-Nuño, Adrián Ramírez-de-Arellano, Pablo César Ortiz-Lazareno, Julio César Villegas-Pineda, Ana Laura Pereira-Suárez, Avraham Eisbruch, Yu-Chao Chang · 2023

Read HPV-Negative and HPV-Positive Oral Cancer Cells Stimulate the Polarization of Neutrophils towards Different Functional Phenotypes In Vitro by Marcela Guadalupe Martínez-Barajas, Luis Felipe Jave-Suárez, Inocencia Guadalupe Ramírez-López, Mariel García-Chagollán, José Sergio Zepeda-Nuño, Adrián Ramírez-de-Arellano, Pablo César Ortiz-Lazareno, Julio César Villegas-Pineda, Ana Laura Pereira-Suárez, Avraham Eisbruch, Yu-Chao Chang (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10741538.txt.

Description

Marcela Martínez-Barajas and colleagues exposed neutrophils to oral cancer signals in 2023. Virus-linked throat cancers are rising worldwide. Oral cancer links to the virus stay debated. Immune cells flood the tumour surroundings there. Neutrophils can help or harm tumours. Cell-line fluids were used as signals.

Virus-positive cancer fluid changed neutrophils one way. Virus-negative fluid activated them more strongly. That strong state may favour tumour growth. A skin-cell fluid gave partial activation only. Some functions woke, others stayed quiet. Tumour-linked neutrophils become therapy targets here. Context decides their functional phenotype. Dish work cannot capture whole tumours.

Catalog record

CREATORMarcela Guadalupe Martínez-Barajas, Luis Felipe Jave-Suárez, Inocencia Guadalupe Ramírez-López, Mariel García-Chagollán, José Sergio Zepeda-Nuño, Adrián Ramírez-de-Arellano, Pablo César Ortiz-Lazareno, Julio César Villegas-Pineda, Ana Laura Pereira-Suárez, Avraham Eisbruch, Yu-Chao Chang
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10741538

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