Non-Intrinsic, Systemic Mechanisms of Cellular Senescence
Rachael E Schwartz, Irina M Conboy, Antonio Musarò · 2023
Read Non-Intrinsic, Systemic Mechanisms of Cellular Senescence by Rachael E Schwartz, Irina M Conboy, Antonio Musarò (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10741531.txt.
Description
Rachael Schwartz and Irina Conboy review how aged blood can push young cells into a spent state, in a survey from 2023. The spent state, senescence, halts cell growth and leaks fire parts that harm kin. Old books blame harm piled up in the cell with time, from inside.
Yet young mice and young dish cells turn spent fast when fed old blood. That fact flips the tale: the spent state can be caught, not just earned. The pair scan what in old blood could do it: proteins, rust sparks, fats, loose code strands, bare or packed in sacs and clumps. If blood-borne sparks spread the state, then blood care, not just cell care, may slow the slide of age.
Catalog record
| CREATOR | Rachael E Schwartz, Irina M Conboy, Antonio Musarò |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |