The Impact of BRAF Mutation Status on Survival Outcomes and Treatment Patterns among Metastatic Colorectal Cancer Patients in Alberta, Canada
R Liam Sutherland, Devon J Boyne, Darren R Brenner, Winson Y Cheung, David Wong · 2023
Read The Impact of BRAF Mutation Status on Survival Outcomes and Treatment Patterns among Metastatic Colorectal Cancer Patients in Alberta, Canada by R Liam Sutherland, Devon J Boyne, Darren R Brenner, Winson Y Cheung, David Wong (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10741517.txt.
Description
Liam Sutherland and co-authors compared survival and treatment for metastatic colorectal cancer patients with and without a BRAF gene mutation in Alberta, Canada, in a 2023 study. The registry-based work covered adults diagnosed from 2017 to 2019 who received at least one round of drug therapy. Of 488 patients, 42 had a confirmed mutation.
The mutated group lived a median of about eight months, against about twenty months for those without the mutation. First-line treatment most often used one of two standard drug combinations in both groups. The authors conclude that the mutation marks a much poorer outlook. That finding strengthens the case for testing every new patient for it.
Catalog record
| CREATOR | R Liam Sutherland, Devon J Boyne, Darren R Brenner, Winson Y Cheung, David Wong |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |