The Intraoperative Administration of Dexmedetomidine Alleviates Postoperative Inflammatory Response in Patients Undergoing Laparoscopy-Assisted Gastrectomy: A Double-Blind Randomized Controlled Trial
Jiae Moon, Duk-Hee Chun, Hee Jung Kong, Hye Sun Lee, Soyoung Jeon, Jooeun Park, Na Young Kim, Hyoung-Il Kim, Hideshi Ishii, Takaaki Hirotsu · 2023
Read The Intraoperative Administration of Dexmedetomidine Alleviates Postoperative Inflammatory Response in Patients Undergoing Laparoscopy-Assisted Gastrectomy: A Double-Blind Randomized Controlled Trial by Jiae Moon, Duk-Hee Chun, Hee Jung Kong, Hye Sun Lee, Soyoung Jeon, Jooeun Park, Na Young Kim, Hyoung-Il Kim, Hideshi Ishii, Takaaki Hirotsu (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10741238.txt.
Description
Jiae Moon and a team of co-authors test whether a sedative given during stomach surgery calms the body's inflammatory surge afterward. Their trial appeared in twenty twenty-three. Surgical stress can weaken immunity in cancer patients and slow recovery.
Eighty-four patients having keyhole stomach surgery were randomized to the drug, dexmedetomidine, or a control. The main marker, C-reactive protein on day one, did not differ between groups. One interleukin marker dipped at the end of surgery in the drug group. Pain scores in recovery and extra painkiller needs in the first hour were also lower. The benefits faded within about two hours. The authors call the anti-inflammatory effect narrow and brief.
Catalog record
| CREATOR | Jiae Moon, Duk-Hee Chun, Hee Jung Kong, Hye Sun Lee, Soyoung Jeon, Jooeun Park, Na Young Kim, Hyoung-Il Kim, Hideshi Ishii, Takaaki Hirotsu |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |