Primary and Secondary Bystander Effects of Proton Microbeam Irradiation on Human Lung Cancer Cells under Hypoxic Conditions
Narongchai Autsavapromporn, Alisa Kobayashi, Cuihua Liu, Aphidet Duangya, Masakazu Oikawa, Tengku Ahbrizal Tengku Ahmad, Teruaki Konishi, Phang Lang Chen, Rabindra Roy · 2023
Read Primary and Secondary Bystander Effects of Proton Microbeam Irradiation on Human Lung Cancer Cells under Hypoxic Conditions by Narongchai Autsavapromporn, Alisa Kobayashi, Cuihua Liu, Aphidet Duangya, Masakazu Oikawa, Tengku Ahbrizal Tengku Ahmad, Teruaki Konishi, Phang Lang Chen, Rabindra Roy (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10741139.txt.
Description
Narongchai Autsavapromporn and co-authors study, in a 2023 paper, how proton beams aimed at a few lung cells can harm nearby cells that were never hit. They test this effect in low oxygen, a state common in lung tumors that resist standard care.
Using a fine proton beam, the team hit a tiny share of cells and then grew hit and unhit cells side by side in layers. They found the harm to nearby cells differed between normal and cancer cells, and between low and normal oxygen. Blockers of cell to cell signals and of a gas signal changed the harm, which points to those signals as carriers.
Catalog record
| CREATOR | Narongchai Autsavapromporn, Alisa Kobayashi, Cuihua Liu, Aphidet Duangya, Masakazu Oikawa, Tengku Ahbrizal Tengku Ahmad, Teruaki Konishi, Phang Lang Chen, Rabindra Roy |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |