Interaction between Gut Microbiota and Dendritic Cells in Colorectal Cancer
Kawther Zaher, Fatemah Basingab · 2023
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Description
Kawther Zaher and Fatemah Basingab offer a 2023 review on how gut microbes interact with dendritic cells in colorectal cancer. This cancer of the colon and rectum is rising worldwide. Its growth is shaped by diet, lifestyle, and the microbes living in the gut. Dendritic cells are immune cells that link the body's first defenses to its targeted ones, and they help decide how the immune system reacts to tumors.
The review explains how an upset balance of gut microbes can steer these cells and, through them, the T cells that attack or spare tumors. It covers disease stages, key checkpoints, and one sensing receptor on young dendritic cells. Drawing on clinical studies, the authors propose pairing dendritic cell vaccines with checkpoint drugs. They argue this pairing could improve how colorectal cancer is treated in years ahead.
Catalog record
| CREATOR | Kawther Zaher, Fatemah Basingab |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |