Genome-Wide Association Analysis Identifies the PMEL Gene Affecting Coat Color and Birth Weight in Simmental × Holstein
Jing Wang, Tingting Fan, Zhenwei Du, Lingyang Xu, Yan Chen, Lupei Zhang, Huijiang Gao, Junya Li, Yi Ma, Xue Gao, Phillip Sponenberg · 2023
Read Genome-Wide Association Analysis Identifies the PMEL Gene Affecting Coat Color and Birth Weight in Simmental × Holstein by Jing Wang, Tingting Fan, Zhenwei Du, Lingyang Xu, Yan Chen, Lupei Zhang, Huijiang Gao, Junya Li, Yi Ma, Xue Gao, Phillip Sponenberg (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10740715.txt.
Description
Jing Wang and co-authors scan the genomes of crossbred cattle for the switches controlling coat color and birth weight, two traits breeders select at a glance. Two hundred thirty-three Simmental-Holstein crosses were genotyped and phenotyped. Nine markers tied significantly to coat color, clustering on one chromosome inside and around a handful of genes.
The PMEL gene, long known for pigment dilution, anchored the strongest signal, with several markers in tight linkage. Birth weight associations were mapped in the same sweep. For crossbreeding programs balancing beef build with dairy ancestry, named loci turn coat and calf size from folklore into selectable genetics, and warn which color genes drag other traits with them.
Catalog record
| CREATOR | Jing Wang, Tingting Fan, Zhenwei Du, Lingyang Xu, Yan Chen, Lupei Zhang, Huijiang Gao, Junya Li, Yi Ma, Xue Gao, Phillip Sponenberg |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |