Inhibition of Cell Apoptosis by Apicomplexan Protozoa–Host Interaction in the Early Stage of Infection
Liyin Lian, Qian Sun, Xinyi Huang, Wanjing Li, Yanjun Cui, Yuebo Pan, Xianyu Yang, Pu Wang · 2023
Read Inhibition of Cell Apoptosis by Apicomplexan Protozoa–Host Interaction in the Early Stage of Infection by Liyin Lian, Qian Sun, Xinyi Huang, Wanjing Li, Yanjun Cui, Yuebo Pan, Xianyu Yang, Pu Wang (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10740567.txt.
Description
Liyin Lian and co-authors review, in a 2023 paper, how single-celled parasites keep host cells alive during early infection. These apicomplexan parasites live inside host cells and cause many diseases in people and animals. If the host cell dies on cue, the parasite loses its home, so it blocks that death.
The review sorts the key parasite proteins and host paths used to stall cell death in the first stage of infection. Each trick helps the parasite survive and multiply inside the cell. Knowing the tricks gives drug and vaccine makers clear targets to aim at. The authors frame the early host-parasite tug of war as a weak point worth attack. The paper gathers a scattered field into one map for future work.
Catalog record
| CREATOR | Liyin Lian, Qian Sun, Xinyi Huang, Wanjing Li, Yanjun Cui, Yuebo Pan, Xianyu Yang, Pu Wang |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |