Role of Specific Autoantibodies in Neurodegenerative Diseases: Pathogenic Antibodies or Promising Biomarkers for Diagnosis

Dimitrina Miteva, Georgi V Vasilev, Tsvetelina Velikova, Buyong Ma · 2023

Read Role of Specific Autoantibodies in Neurodegenerative Diseases: Pathogenic Antibodies or Promising Biomarkers for Diagnosis by Dimitrina Miteva, Georgi V Vasilev, Tsvetelina Velikova, Buyong Ma (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10740538.txt.

Description

Dimitrina Miteva and colleagues published a 2023 review of autoantibodies in diseases that destroy brain cells, such as Alzheimer's and Parkinson's. In these illnesses, misfolded proteins build up, neurons die, and the immune system produces antibodies against the body's own molecules. The review asks whether those antibodies help cause the damage or merely signal it.

Evidence suggests some antibodies do contribute to harm, including stripping insulation from nerve fibers and worsening thinking problems. Others may serve as early warning markers in blood tests. Sorting the harmful from the merely informative could open new routes to earlier diagnosis and treatment.

Catalog record

CREATORDimitrina Miteva, Georgi V Vasilev, Tsvetelina Velikova, Buyong Ma
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10740538

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