Molecular Machines For The Control Of Transmembrane Transport

Toby G Johnson, Matthew J Langton · 2023

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Description

Toby Johnson and Matthew Langton wrote this 2023 perspective on tiny machines that work inside cell-like membranes. Nature parks some of its best machinery, like ion pumps, in the fatty films that wrap cells. Chemists hope to copy that trick with synthetic machines whose moving parts pump ions across the film on demand.

The authors survey the designs built so far. Some machines switch shape when triggered, others run like motors, and some ferry ions while anchored or drifting in the film. Interlocked ring-and-thread molecules feature as well. The piece weighs what these systems must learn from their natural cousins, and where controlled ion flow could pay off, from sensing to medicine.

Catalog record

CREATORToby G Johnson, Matthew J Langton
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE60 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10740008

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