New synthetic cannabinoids and the potential for cardiac arrhythmia risk

Jules C Hancox, Caroline S Copeland, Stephen C Harmer, Graeme Henderson · 2023

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Description

Jules Hancox and three co-authors assess new synthetic cannabis-like drugs in a 2023 paper. These drugs have been linked to a longer heart signal interval, which can raise the risk of dangerous rhythms. Hard data are scarce because new versions appear fast and research access is limited.

The team used two learning-based tools to test how seven new compounds might act on a key heart channel. Five were flagged by both tools as likely blockers of that channel, and one looked especially strong. Two others gave mixed readings. The authors say the results point to a real rhythm risk and call for detailed safety checks.

Catalog record

CREATORJules C Hancox, Caroline S Copeland, Stephen C Harmer, Graeme Henderson
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE16 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10739592

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