Bioinformatics and system biology analysis revealed the crosstalk between COVID‐19 and osteoarthritis
Bowen Lai, Heng Jiang, Taotao Liao, Yuan Gao, Xuhui Zhou · 2023
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Description
Bowen Lai and others put out a 2023 computer analysis linking COVID and osteoarthritis. Doctors noticed both getting worse together. Shared biology might explain the overlap. The team mined gene data sets from both diseases. Networks flagged common genes and pathways.
Seventy-four genes changed in both diseases. Four stood out as hub genes. Their levels gave a fair read on disease status. Mouse joint tissue backed the signals. Immune cell patterns were also set side by side. Possible drugs emerged from data bank matching. Shared paths could guide joint care for sick patients. Checking in real patient samples remains the next step.
Catalog record
| CREATOR | Bowen Lai, Heng Jiang, Taotao Liao, Yuan Gao, Xuhui Zhou |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |