The regulatory effect of growth differentiation factor 11 on different cells
Yingchun Shao, Ting Liu, Xiaobo Wen, Renshuai Zhang, Xinlin Liu, Dongming Xing · 2023
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Description
Yingchun Shao and five co-authors review a growth factor in two thousand twenty-three. The factor, GDF11, is found in many tissues and has shown effects against heart aging and tumors in past research. Drug versions are in development, from an approved-path antibody to early-stage candidates.
The review sums up what GDF11 does in different cell types and where the debates and problems lie. Commercial interest in anti-aging and regenerative uses has run ahead of the science, the authors warn. Sorting out which cells the factor acts on is key to judging its promise and risks. They aim to give a balanced reference for building safer treatment strategies around the factor.
Catalog record
| CREATOR | Yingchun Shao, Ting Liu, Xiaobo Wen, Renshuai Zhang, Xinlin Liu, Dongming Xing |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |