SYSTEMS BIOLOGY OF HUMAN AGING - NETWORK MODEL 2023

John Furber · 2023

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Description

John Furber presents a 2023 network model of human aging, drawn as a large linked diagram. The model maps causes of aging inside and outside cells, from gene damage to stiff blood vessels. It also marks feedback loops where one harm feeds another, plus lifestyle factors and possible therapies.

Chains in the model run from DNA breaks and shortened chromosome caps to cell death, tissue loss, and organ failure. Waste build-up in cell compartments and clogged protein cleanup get key roles. So do swelling cascades from damaged tissue. Furber keeps the diagram online as a shared reference for researchers and students. It is offered as a thinking aid, not as proof of any one therapy.

Catalog record

CREATORJohn Furber
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10738645

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