GEROSCIENCE BLOOD-BASED BIOMARKER INDICES AND PHYSICAL PERFORMANCE IN OLDER ADULTS

Denise Houston, Deeya Pathak, Rebecca Neiberg, Jamie Justice, Barb Nicklas, Michael Miller · 2023

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Description

Denise Houston and co-authors link blood markers of aging to physical ability in older adults, in this 2023 paper. The geroscience idea holds that worn cell and molecular systems drag down strength and speed. The team built three combined scores from five blood measures tied to inflammation and stress response, then compared them with walking and strength tests.

Four hundred fourteen adults, average age about seventy-seven, took part. The three scores agreed closely with each other. Higher scores, meaning worse marker profiles, went with slower walking over both short and long courses. Links with a full performance battery were a bit stronger for two of the scores, while grip strength showed only weak ties. The authors conclude that combined marker scores track real-world function and could help flag older adults at risk of decline.

Catalog record

CREATORDenise Houston, Deeya Pathak, Rebecca Neiberg, Jamie Justice, Barb Nicklas, Michael Miller
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10738256

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