TRANSCRIPTOMIC SIGNATURES OF AGING, GENETICS, AND MORTALITY RISK: FINDINGS FROM THE LONG LIFE FAMILY STUDY
Mary Wojczynski, Nancy Glynn, Nalini Raghavachari · 2023
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Description
Mary Wojczynski, Nancy Glynn, and Nalini Raghavachari read gene activity for clues to long life in this 2023 paper. The Long Life Family Study follows families rich in very old members. It enrolled 4,953 people from 539 families, across two generations.
Visits measured strength, thinking, and blood markers, with a second round years later. This paper focuses on transcriptomic signatures: patterns of gene activity tied to aging, inheritance, and death risk. Families who age slowly offer a natural experiment. Genes turned up or down in them may reveal protective biology. The findings could steer healthy aging research toward the pathways that matter most.
Catalog record
| CREATOR | Mary Wojczynski, Nancy Glynn, Nalini Raghavachari |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |