ASSOCIATION OF DIABETES WITH BODY COMPOSITION, CARDIORESPIRATORY FITNESS, AND MITOCHONDRIAL ENERGETICS

Sofhia Ramos, Giovanna Distefano, Philip Kramer, Peggy Cawthon, Frederico Toledo, Steven Cummings, Bret Goodpaster, Paul Coen · 2023

Read ASSOCIATION OF DIABETES WITH BODY COMPOSITION, CARDIORESPIRATORY FITNESS, AND MITOCHONDRIAL ENERGETICS by Sofhia Ramos, Giovanna Distefano, Philip Kramer, Peggy Cawthon, Frederico Toledo, Steven Cummings, Bret Goodpaster, Paul Coen (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10737810.txt.

Description

Sofhia Ramos and co-authors link diabetes to fitness and muscle energy in older adults in a 2023 study. Nearly nine hundred participants of a muscle and aging study, averaging in their late seventies, underwent deep phenotyping. About one in seven reported diabetes.

Muscle bulk itself looked similar between groups, but fat inside the belly and inside muscle ran higher with diabetes. Peak oxygen uptake and every measure of mitochondrial energy output ran lower. The differences survived adjustment for body size and other illness. The picture blames energy machinery and fat placement, not muscle amount, for diabetic frailty.

Catalog record

CREATORSofhia Ramos, Giovanna Distefano, Philip Kramer, Peggy Cawthon, Frederico Toledo, Steven Cummings, Bret Goodpaster, Paul Coen
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10737810

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